recently showed that overexpression of PTRF in primary glioblastoma cells results in accumulation of lysophosphatidylcholine (LPC) species and decreased phosphatidylcholine (PC), resulting in increased membrane fluidity, endocytosis, and levels of the protein cytoplasmic phospholipase A2 (cPLA2), which provides fatty acids for mitochondrial fatty acid oxidation. The gene discussed is CAVIN1; the disease is glioblastoma.