PPARGC1A and gastric cancer: Moreover, Wu et al. (31) observed that overexpression of HCP5 could interact with miR-3619-5p, which upregulated peroxisome proliferative activated receptor gamma (PPARG) coactivator 1 alpha (PPARGC1A) through miR-3619-5p/the AMP-activated protein kinase (AMPK)/transcription complex peroxisome proliferator-activated receptor (PPAR) coactivator-1α (PGC1α)/enhancer-binding protein beta (CEBPB) axis, regulating 5-Fluorouracil (5-Fu) and oxaliplatin resistance in gastric cancer.