EGFR and nasopharyngeal carcinoma: Epidermal growth factor receptor (EGFR) is also highly expressed in NPC (39) and a previous study has shown that the application of cetuximab (CTX) or nimotuzumab (NTZ) (anti-EGFR monoclonal antibodies) was a significant protective factor for OS, DFS, and DMFS in patients treated with CCRT (40).