In multivariate analysis, lymph node-positive CRC patients also demonstrated that elevation of the TNM stage (OR, 3.157; 95% CI, 2.445–4.077; P < 0.001), CRP/MCV ratio (OR: 1.512, 95% CI: 1.091–2.094, P = 0.013), and differentiation (OR: 1.452, 95% CI: 1.184–1.779, P < 0.001) were significant risk factors (Figure 6). Here, CRP is linked to colorectal carcinoma.