CEACAM5 and colorectal carcinoma: For the whole CRC population, univariate logistic regression analysis showed that 12 potential predictors had a significant association with dMMR, including age, histology, tumor location, tumor size, degree of differentiation, T stage, harvested lymph nodes, positive lymph nodes, perineural invasion, lymphovascular invasion, CEA and CA 72-4 (Table 5).