CXCL8 and cystic fibrosis: In our study, we found that median CF sputum and CF plasma NE were not significantly different in PA and non-PA groups, however, a tendency for higher values was observed in PA positive group as compared to PA negative group. Sagel et al. demonstrated higher neutrophil count, IL-8, and NE levels in BAL samples of patients with CF harbor PA as compared to those with negative for PA and positive for other pathogens [24].