Dysregulated sleep and OSA are associated with increased circulating concentrations of proinflammatory cytokines, including interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF)-α (Faraut et al., 2012), which are important molecular signatures of a pro-inflammatory response (Ashley, Weil & Nelson, 2012). The gene discussed is TNF; the disease is obstructive sleep apnea syndrome.