CDK1 and cancer: Furthermore, cell cycle of cancer cell lines is detained by halting the expressions of cyclin D1, cyclin B1, and cyclin dependent kinase 1 (CDK1), apoptosis induction, and enhancement in Bax/Bcl-2 (B-cell lymphoma 2) ratio and caspase-3 cleavage, with these noticeable mechanistic routes being related to anticancer ability of wogonin [22].