ANGPT2 and septic shock: A research found that the decline of angiopoietin-2 (Ang-2) and EVLWI in sepsis patients was complicated by acute respiratory distress syndrome (ARDS), which was significantly related to the reduced death rate at 24 hours after admission [36]; this finding was similar with another study describing that, after 72 hours of treatment of high-volume hemofiltration (HVHF), the increase of EVLWI and PVPI was negatively correlated with the survival rate of patients with septic shock [37].