INS and type 2 diabetes mellitus: For example, Gegen Qinlian Decoction, composed of Coptidis Rhizoma, Scutellariae Radix, Puerariae Lobatae Radix, and Glycyrrhizae Radix et Rhizome, is a classic traditional Chinese medicine prescription that is widely used to clinically treat diabetes mellitus, and it has been proved that it can significantly reduce blood glucose and increase serum insulin level in type 2 diabetic mice [51].