These are six HLA class II genes (HLA-DQB1, -DQA1, -DRB1 and the paralogues -DQB2, -DQA2, and -DRB5) in line with known associations of T1D with HLA-DR/DQ haplotypes (Erlich et al., 2008) as well as PRRT1. Additionally, the classical HLA-DRA and the non-classical HLA-DO gene, the peptide transporters TAP1 and TAP2 involved in HLA class I antigen processing, the HLA-DO/TAP2 read-through variant AL669918.1 and 14 non-HLA-genes are significantly associated after Bonferroni correction. The gene discussed is HLA-DRB1; the disease is type 1 diabetes mellitus.