HK2 and posterior cortical atrophy: DeWaal et al. (2018) demonstrated that deficiency in HKII inhibited glycolysis metabolism of hepatocellular carcinoma and promoted OXPHOS and chemotherapy-sensitivity of hepatocellular carcinoma. A large number of experiments have confirmed that serum HKII is helpful for the detection and prognosis of PCA (Mao et al., 2018).