Since the discovery of the CFTR gene in 1989 (Kerem et al., 1989), we are now able to diagnose cystic fibrosis (MIM: 602421) rapidly, predict pancreatic functional status, and plan preventative care with modulator therapy (Ramsey et al., 2011; Farrell et al., 2020). This evidence concerns the gene CFTR and cystic fibrosis.