For this reason, a strategy to control the infection by COVID-19 could result in inhibiting initial stages of infection and dissemination of pathogens in the DCs through DC-SIGN, as it has been demonstrated by the oral AM3 administration (44) AM3 acts, dose dependently, on MDDCs by blocking the adhesion of pathogens such as Candida spp., Aspergillus spp. Here, CD209 is linked to infection.