In the hyperinflammatory phase, patients with severe COVID-19 exhibit higher levels of IL-2, IL-6, IL-7, IL-10, IP-10, MCP1, TNF-α, macrophage inflammatory protein 1 alpha (MIP1A), and granulocyte-colony stimulating factor (G-CSF) than patients with moderate infections (early inflammatory phase). This evidence concerns the gene TNF and infection.