CD40LG and autoimmune polyendocrinopathy: Also, when looking at multiple criteria aPL positive test (considering IgG and/or IgM isotypes), the APS group had significantly higher rates of double aPL positive testing [43.7% vs. 8% (COVID-19) and vs. 18.4% (infections)], triple aPL positive testing [40.2% vs. 2.2% (COVID-19) and vs. 8% (infections)].