IGHE and hepatitis B virus infection: The fusion protein consisting of the non-allergenic IgE epitope-derived peptides of the allergen and an unrelated carrier (i.e., hepatitis B-derived preS in case of the BM vaccines) can then be used to induce IgG antibodies toward the IgE epitopes of the allergen which block allergic reactions by interfering with the IgE recognition of the allergen.