HPSE and chronic gastritis: To evaluate the impact of heparanase on the infiltration of immunocytes into the lamina propria of H. pylori-infected chronic gastritis mucosa, we evaluated (RT-qPCR) the expression of markers specific for the different immune cell populations, including NK1.1 and GranB (NK cells), Langarin (dendritic cells), F4/80 (macrophages), and Ly6g (neutrophils).