As Qalb is elevated in almost every other patient with myelin oligodendrocyte glycoprotein (MOG)-associated disorders (MOGAD) (26) or aquaporin-4 positive Neuromyelitis optica spectrum disorder (NMOSD) (27), a correct age-dependent interpretation is important in differential diagnosis of CNS demyelinating diseases. The gene discussed is MOG; the disease is neuromyelitis optica.