IFNL3 and infection: To analyze the association between these SNPs and susceptibility to HCV infection, Group B and Group C patients were combined into the HCV-infected group and compared them with the control Group A. After adjusting for gender, age, ALT, AST, IL28B-rs12979860, IL28B-rs8099917, and route of infection, the results of logistic regression analysis revealed that KIR2DS4-rs35440472 and HLA-C-rs1130838 were associated with susceptibility to HCV infection.