LDLRAP1 and familial hyperaldosteronism: FH is commonly caused by mutations in one of the four genes in the LDL-C metabolic pathway, namely low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), proprotein convertase subtilisin/kexin type 9 (PCSK9) and low density lipoprotein receptor adaptor protein 1 (LDLRAP1) (2, 3).