MAPT and early-onset autosomal dominant Alzheimer disease: We also correlated signals that were extracted from areas of significant FC with cerebrospinal fluid biomarkers, including Aβ1-40, Aβ1-42, Aβ1-40/Aβ1-42, t-tau, and p-tau, which be used as one of the differentiations and diagnostic criteria for Alzheimer's disease (80).