As shown in GO terms, the upregulated genes were most significantly enriched in the CC of extracellular region, the BP of muscle contraction, and the MF of actin filament binding, fibronectin binding, calcium ion binding, etc. The actin-associated GO terms may relate to the development of ectopic lesions of endometriosis (Figure 6A). This evidence concerns the gene FN1 and endometriosis.