Also, experimental myocardial infarction in Wistar rats and levels of cardiac IL-1β, IL-6, and IL-2 were associated with antiapoptotic and anti-inflammatory mechanisms by compound 21 (Kaschina et al., 2008), and compound 21 prevented vascular inflammation in vitro and in vivo (Sampson et al., 2016). The gene discussed is IL1B; the disease is myocardial infarction.