Also, experimental myocardial infarction in Wistar rats and levels of cardiac IL-1β, IL-6, and IL-2 were associated with antiapoptotic and anti-inflammatory mechanisms by compound 21 (Kaschina et al., 2008), and compound 21 prevented vascular inflammation in vitro and in vivo (Sampson et al., 2016). This evidence concerns the gene IL6 and myocardial infarction.