Fecal calprotectin levels above 250 mcg/g correlated with female sex (R = 0.457, p = 0.042), LCIG treatment (R = 0.5, p = 0.018) and high serum C reactive protein (CRP) (R = 0.677, p = 0.011), while levels above 150 mcg/g inversely correlated with self-reported hyposmia (R = −0.567, p = 0.006); increased fecal calprotectin also correlated with body mass index (BMI) (R = 0.499, p = 0.018) and obesity (R = 0.490, p = 0.02). Here, CRP is linked to obesity due to melanocortin 4 receptor deficiency.