TNFα exhibits antitumor effects through activation of programmed cell death [44] and migration and invasion of breast cancer cells through activation NF-κB-dependent EMT-inducing transcription factors (EMT-TFs) such as Twist1, Snail, Slug, and Zeb1/2 that drive inactivation of E-cadherin. This evidence concerns the gene ZEB1 and breast carcinoma.