BCL2 and acute myeloid leukemia: In this study, the expression level of Bax was notably inhibited, and Bcl2 was significantly up-regulated owing to down-regulation of MT2A expression, suggesting that MT2A will induce HL60 cell apoptosis by regulating the dynamic changes of Bax and Bcl2 proteins and participate in the occurrence and development of AML through the apoptotic signal network.