NFKB1 and familial pancreatic carcinoma: MiR-628-5p functions as a tumor-suppressive microRNA (miRNA) in pancreatic cancer by negatively regulating phospholipid scramblase 1 and insulin receptor substrate 1 expression, which inhibits NF-κB signaling.76 Furthermore, NF-κB is reported to be involved in antitumor immunity.