AKT1 and cancer: Signaling pathways (e.g., RAS, phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), janus kinase (JAK)/signal transducer and activator of transcription (STAT), Hippo/yes-kinase-associated-protein (YAP), Wingless/int1 (WNT), etc.)have been linked to a variety of cancer-related cellular processes, including cell proliferation, differentiation, apoptosis, migration, angiogenesis, metabolism, and immune regulation.