Evidence from Safa et al. [167], Chen et al. [168], Zhou et al. [169], Hu et al. [170], Lou et al. [171], Zhang et al. [172] and Chen et al. [173] study indicated that the expression of CCL22, CCR1, FPR1, KNG1, CRISPLD2, CD38 and GPRC5A were linked with progression of ischemic heart disease. The gene discussed is KNG1; the disease is coronary artery disorder.