41例T-ALL患者中24例(58.5%)具有NOTCH1和(或)FBXW7(N/F)基因突变。其中NOTCH1突变患者17例(41.5%),FBXW7突变患者10例(24.4%),同时合并两种突变者3例(7.3%)。. This evidence concerns the gene NOTCH1 and acute lymphoblastic leukemia.