Notably, AHB, HCC, and CHB individuals’ PBMCs produced higher levels of IFN-γ after CCL19 stimulation, compared with negative control (NC, without CCL19 and HBc stimulation), while produced poor secretion of IFN-γ after HBc stimulation, and the role of CCL19 is also weakened (Supp. Here, KRT88P is linked to hepatocellular carcinoma.