FTO and colorectal cancer: To investigate the relationship between FTO and the metastasis-related phenotype, we first detected the protein level of FTO in 11 colorectal cancer cell lines (HCT8, HCT116, HCT15, DLD1, RKO, SW480, SW620, Ls174t, CW-2, LoVo, and HT-29) and chose two cell lines with different FTO levels, HCT116 and DLD1, for further experiments (Fig. 2A, Supplementary Information: Fig. S2A).