To explore if LINC00511 knockdown led to a decrease in the expression of PKM2, LINC00511-depleted A2058 melanoma cells were analysed via qRT-PCR and a significant decrease in PKM2 expression was observed, whereas no decrease in PKM2 expression was seen in either SFPQ- or LINC01234-depleted cells (Fig. 4c and Fig. S2). Here, PKM is linked to melanoma.