Whereas in colorectal, lung and renal cancer SFPQ has been reported to act as a transcriptional repressor that serves to dampen proto-oncogene expression, a function that is frequently derailed via the overexpression and binding of oncogenic lncRNAs, such as MALAT-1 [38] and SANT1 [15]. This evidence concerns the gene MALAT1 and renal carcinoma.