Considering that Nrf2 function is impaired in mitochondria-related disorders, including PD [20], and the high oxidative load in park, Pink1 KD flies, we OE cncC/Nrf2 ubiquitously (Supplemental Fig. 6a) (Gal4Tub) in park and Pink1 RNAi expressing flies. The gene discussed is PINK1; the disease is Parkinson disease.