To sum up, the prognostic value of CEA was identified in COVID-19 patients and the developing neutrophils/neutrophil progenitors (highly expressed CEACAM8, ELANE and LYZ) could have the cross talk with type II pneumocyte (highly expressed CEACAM5 and CEACAM6) via CEACAM8-CEACAM6. Here, CEACAM5 is linked to COVID-19.