miR-650 binds directly to the 3′UTR of ras-related estrogen-regulated growth inhibitor (RERG) and activates the AKT/ERK/NF-κB pathway mediated by the RERG/PH Domain Leucine-rich Repeat Protein Phosphatase (PHLPP) 2 complex to promote the growth of glioblastoma multiforme [38]. This evidence concerns the gene PHLPP1 and glioblastoma.