It has been revealed that Cdc37/Hsp90 complex positively regulates viral infection by maintaining the stability of P, but not N. Results of that research demonstrated that Cdc37 co-chaperone helped P to load onto the Hsp90 machinery, with or without Cdc37 binding to Hsp90, thereby regulating P stability. This evidence concerns the gene HSP90AA1 and viral infectious disease.