RDH12 and Leber congenital amaurosis: Variants in the retinol dehydrogenase 12 (RDH12) gene are commonly associated with Leber congenital amaurosis (LCA), a severe retinal dystrophy characterised by night blindness, nystagmus and central loss of vision in early childhood, eventually leading to complete blindness in adulthood (Fahim et al., 2019).