LDLR and atherosclerosis: lactis CUL34 (NCIMB 30172) in combination with L. plantarum CUL66 (called Lab4P hereafter) reduced plasma levels of total cholesterol and suppressed diet‐induced weight gain.[5] More recently, Lab4P was shown to reduce body weight and improve well‐being in a randomized control trial of overweight and obese adults.[6] However, the effects of Lab4P on atherosclerosis are not known and were investigated using LDL receptor deficient (LDLr−/−) mice fed HFD for 12 weeks.