The genetic causes of FSGS were shown including COQ8B (AR, 3), TRPC6 (AD, 2), PAX2 (AD,3), NPHS2 (AR,1), NUP160 (AR,1), WT1 (AD, 1) and UMOD (AD, 1). Here, NPHS2 is linked to focal segmental glomerulosclerosis.