SOX2-OT and non-small cell lung carcinoma: Further in vitro studies demonstrated that knockdown of lncRNA-SOX2OT expression in NSCLC cell lines decreased the cellular and exosomal expression of lncRNA-SOX2OT and reduced the delivery of exosomal lncRNA-SOX2OT to recipient RAW264.7 cells, which demonstrated important communication between tumour cells and osteoblasts via the transport of exosomal lncRNA-SOX2OT.