Lee et al. [38] proposed a CT response criterion based on consideration of tumor components (GGO and solid part) and the presence of cavitation, necrosis, and attenuation changes for response assessment in NSCLC patients who underwent epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) thertabapy (Figs. 5 and 6). This evidence concerns the gene EGFR and non-small cell lung carcinoma.