The analysis of a public RNAseq data set generated from the Mount Sinai Brain Bank (MSBB) cohort [31] suggested that SETD7 expression is slightly increased in the parahippocampal cortex of demented patients (clinical dementia rating (CDR) 3–5) compared to both patients with mild cognitive impairment (MCI, CDR 1–2) and non-demented donors (CDR 0–0.5), but fold changes (FC) are small (FC 1.15, false discovery rate (FDR) 0.005 for demented vs. MCI, FC 1.13 and FDR 0.012 for demented vs. non-demented, Suppl. This evidence concerns the gene SETD7 and Cognitive impairment.