Although many biomarkers for GC including carbohydrate antigen 72–4 (CA72-4), alphafetoprotein, carbohydrate antigen 12–5 (CA12-5), SLE, BCA225, hCG and pepsinogenI/II have been reported, carcinoembryonic antigen (CEA) and carbohydrate antigen 19–9 (CA19-9) are still the most frequently used biomarkers in clinical practice for GC [5]. This evidence concerns the gene CEACAM5 and systemic lupus erythematosus.