MAFB and Bardet-Biedl syndrome: For example, HES2, MAFB, RPS12, RPL12, RPS15, and AFF2 are all associated with cancer [63–66], whereas BBS12 is a gene related to Bardet-Biedl Syndrome, a multi-organ genetic disease that can involve hypoplasia of the uterus, ovaries, and fallopian tubes [67].