To further confirm the depression‐like behaviour induced by mitophagy and apoptosis was associated with Glu‐GluR2‐Parkin pathway, we also prepared DD model and used transmission electron microscope to evaluate mitophagy and autophagosome and applied Western blot assay to detect the expression of Glu‐GluR2‐Parkin pathway protein and the endogenous apoptosis protein of Cyt‐c. This evidence concerns the gene PRKN and dentin dysplasia.