The resistance to oxaliplatin in colon cancer cell lines was identified in Fig. S1C. Oxaliplatin‐resistant cell lines, including sw480‐lohp and HCT116‐lohp, expressed higher CPT1A (Fig. 3B) and oxaliplatin (2 μg·mL−1), stimulated the protein and mRNA levels of CPT1A in these cell lines (Fig. 3C,D). Here, CPT1A is linked to colonic neoplasm.