Madiraju et al. deposited three patents showing that ABHD6 activityis tightly correlated to insulin secretion and to conversion of whiteinto brown adipose tissue.112−114 In particular, the three patentsdescribed ABHD6 inhibitors which promoted insulin secretion by increasingthe accumulation of MAGs and that may be useful for the treatmentof type-2 diabetes, insulin resistance and metabolic syndrome. This evidence concerns the gene INS and metabolic syndrome.