It is possible that lncRNA HULC may enhance the HIP‐1α‐related PI3K/AKT/mTOR signaling, which cross‐talks with the Wnt/β‐catenin signaling to upregulate TGF‐β and Snail expression, promoting the EMT process in GBM cells.21, 22, 23. Here, SNAI1 is linked to glioblastoma.