Neutrophils were recruited to the periphery of the glioma inflammatory region via chemokines including CXCL1/2/3/5/6 and IL-8 (CXCL8), which were secreted from glioma cells due to the expression of IL-1β (Lee S.Y. et al., 2017; Mostofa et al., 2017). This evidence concerns the gene IL1B and central nervous system cancer.