The expression of CDH6, DPYSLE3, GJA1, IL15, and ACTA2 is also relevant to survival in many types of cancers, but its mechanism of action in CRC requires further study to explore its impact (Looyenga et al., 2013; Ji et al., 2018; Sun et al., 2018; Baek et al., 2019). This evidence concerns the gene ACTA2 and colorectal carcinoma.